Meropenem Injection is an antibiotic. It is used to treat infections of the skin, stomach, and meningitis (infection of the membrane that surrounds the brain and spinal cord). It works by killing the bacteria that cause infection.
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Merobac 1gm Injection contains Meropenem, an antibiotic used to treat various bacterial infections such as pneumonia, urinary tract infections, intra-abdominal infections, gynecological infections, skin infections, meningitis, and septicemia. It is also used in febrile neutropenia and bacterial infections in neutropenic patients.
During the treatment, your doctor may conduct blood tests periodically. Caution is advised in patients with liver problems, kidney problems, and diarrhea.
Merobac 1gm Injection is not recommended in patients with gastrointestinal problems and hypersensitivity reactions. Pregnant or breastfeeding women should consult their doctor before using it.
Use with caution in children over 3 months old and geriatric patients.
Common side effects may include abdominal pain, nausea, vomiting, diarrhea, headache, skin rash, itching, pain, and inflammation. If any of these symptoms persist, consult your doctor for further guidance.
Alcohol consumption should be avoided as it might further reduce alertness and cause excessive drowsiness.
Merobac 1gm Injection should not be used in pregnancy unless the benefit justifies the potential risk to the fetus. Consult your doctor before receiving it.
Merobac 1gm Injection should not be used in breast-feeding women unless the benefit justifies the potential risk to the baby. Consult your doctor before receiving.
There is no data available, but it is anticipated that Merobac 1gm Injection will not affect the ability to drive and use machines.
Merobac 1gm Injection should be taken with caution in patients with kidney problems. If needed dose will be adjusted accordingly. Consult your doctor before receiving.
Merobac 1gm Injection should be used with caution in patients with liver problems. Consult your doctor before receiving.
Used to treat bacterial infections such as:
Merobac 1gm Injection is a broad-spectrum carbapenem antibiotic that is active against gram-positive and gram-negative bacteria. It exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death.
Merobac 1gm injection is used to treat bacterial meningitis, an inflammation of the protective membranes surrounding the brain and spinal cord caused by Streptococcus pneumoniae and Neisseria meningitidis. It also treats skin and structure infections like cellulitis and wound infections caused by Streptococcus pyogenes and Staphylococcus aureus. In addition, it prevents intra-abdominal infections caused by Escherichia coli and Klebsiella, as well as cures pneumonia, a lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.
Meropenem is a carbapenemic antibiotic for parenteral use. It exerts its bactericidal effect by interfering with the synthesis of bacterial cell walls. It penetrates the walls of bacterial cells, is very stable to all serine β-lactamases, and has a significant affinity for penicillin-binding protein (PBP). It shows effective bactericidal activity against a broad spectrum of gram-positive and gram-negative bacteria, aerobic and anaerobic bacteria.
The recommended daily dosage of Merobac 1gm Injection is as follows:
For Adults:
For Children (3 months to 12 years):
Meropenem should be administered by intravenous infusion over approximately 15-30 minutes or as an intravenous bolus (5 to 20 ml) over approximately 3-5 minutes. The dosage and duration of therapy should be established depending on the type, severity of infection, and the patient's condition. Please consult your healthcare provider for the appropriate dosage for your specific condition.
Probenecid can affect the elimination of meropenem by inhibiting its renal excretion, leading to an increase in the plasma concentration and prolonging its elimination half-life. This interaction may require dose adjustments or monitoring when both medications are used together.
It's important to note that meropenem can also reduce serum levels of valproic acid, potentially leading to subtherapeutic levels of valproic acid in some patients. Monitoring of valproic acid levels and adjustment of the dose may be necessary if meropenem is co-administered with valproic acid.
As with any medication, it's crucial for healthcare providers to be aware of potential drug interactions and carefully monitor patients when multiple drugs are used together to ensure the effectiveness and safety of treatment. Patients should always inform their healthcare provider about all the medications they are taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions and ensure the best possible treatment outcomes.
Patients who are allergic to this product should not use meropenem.
Merobac 1gm Injection is classified as Class B in pregnancy. This means that there are no adequate and well-controlled studies of pregnant women using this drug. Therefore, Merobac 1gm Injection should be used during pregnancy only when clearly necessary, and the potential benefits must be weighed against the potential risks to the unborn baby.
Additionally, caution should be exercised when administering Merobac 1gm Injection to breastfeeding women. Since many drugs are excreted in human milk, the use of Merobac 1gm Injection should be carefully considered, and the potential risks to the nursing baby should be evaluated before administering the medication to breastfeeding mothers.
As always, pregnant and breastfeeding women should consult with their healthcare provider before using any medication to ensure the safety and appropriateness of its use during this period.
Merobac 1gm Injection should be used with caution in patients with underlying central nervous system (CNS) disorders such as brain lesions or a history of seizures. It is not recommended for the treatment of Methicillin-resistant Staphylococcus aureus (MRSA) infections. Extra caution should be exercised when using the medication in patients with renal impairment. The use of Merobac 1gm Injection is not recommended in children, during pregnancy, and lactation due to limited safety data.
Monitoring Parameters:
Regarding lactation, it is unknown whether the drug is excreted in breast milk, so Merobac 1gm Injection should be used with caution in lactating women.
Please consult with a healthcare professional for appropriate monitoring and to determine the suitability of Merobac 1gm Injection for specific patient conditions.
Vial store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children.
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